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Choosing Your First ED Medication

Understanding your options and finding the right fit

If you're considering ED treatment for the first time, most prescribers will recommend starting with a standard on-demand dose — typically Sildenafil 50mg, Tadalafil 10mg, or Vardenafil 10mg. Each works slightly differently in terms of onset, duration, and side-effect profile, so your choice may depend on lifestyle and personal preference.

What to expect

ED medications typically take 30–60 minutes to take effect. Common side effects include headache, flushing, and nasal congestion. These are usually mild and short-lived. Avoid taking them with a heavy meal, as this can delay absorption.

Getting your prescription

Since 2018, Sildenafil has been available over the counter in the UK as Viagra Connect. For other ED medications, you'll need a prescription. Most online pharmacies listed here offer discreet consultations — some include this free of charge.

Generics save money

Generic Sildenafil, Tadalafil, and Vardenafil are clinically equivalent to branded Viagra, Cialis, and Levitra but significantly cheaper. All pharmacies listed here dispense UK-licensed generics unless otherwise stated.

Quick tips

  • Start with the standard dose — your prescriber can adjust up or down based on your response
  • Try a medication at least 4–8 times before deciding it doesn't work for you
  • Avoid alcohol and heavy meals before taking on-demand treatments
  • All medications listed require sexual stimulation to work — they do not cause automatic erections

Best prices for this stage

Sorted by total cost including consultation fees.

All pharmacies GPhC registered